Comparing the effect of levofloxacin with azithromycin in improving pulmonary function of patients with bronchiectasis
- Conditions
- Bronchiectasis.Bronchiectasis with (acute) exacerbationJ47.1
- Registration Number
- IRCT20100102002954N28
- Lead Sponsor
- Shahroud University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 72
Patients with definite diagnosis of aggravated non-fibrocystic bronchiectasis disease;
Not having moderate to severe heart failure (EF>50);
Stable vital signs;
Having a controlled and stable drug regimen (according to the opinion of a pulmonologist) during the study;
Informed consent to participate in research.
Gastrointestinal problems such as severe nausea and vomiting;
The presence of various cancers of the respiratory system;
The presence of chronic kidney and liver disease at the same time;
History of any surgery on the respiratory system at least in the last year;
A history of receiving any antibiotics in the last month;
A history of receiving any corticosteroid drugs in the past month;
Pregnancy and breastfeeding.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measuring oxygen saturation (o2sat). Timepoint: Once every two weeks. Method of measurement: Standard method with pulse oximetry device.;Measurement of lung volumes and capacities. Timepoint: Once every two weeks. Method of measurement: Standard method with spirometer.
- Secondary Outcome Measures
Name Time Method Measuring discomfort from breathing (Dyspnea). Timepoint: Once every two weeks. Method of measurement: Using standard Borg questionnaire.;Measurement of white blood cells. Timepoint: Once every two weeks. Method of measurement: By standard laboratory method.