Treating PTSD and alcohol use disorder simultaneously

Not Applicable

Completed

• Conditions: Post-traumatic stress disorder and alcohol use disorder; Mental and Behavioural Disorders; Post-traumatic stress disorder and Mental and behavioural disorders due to use of alcohol

• Registration Number: ISRCTN61391164
• Lead Sponsor: Rosenlunds sjukhus [Rosenlund Hospital]

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-06
• Study Completion: 2021-05-10
• Last Update Posted: 10 January 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

1. Female
2. Aged 18 years or older
3. Current PTSD and moderate to severe AUD, according to DSM-5 and clinical assessment

Exclusion Criteria

1. Current moderate to severe SUD, other than alcohol and nicotine, according to DSM-5
2. Current or not stably treated psychosis
3. Suicidal or homicidal ideation deemed to be in need of treatment before study treatment can start
4. Current medication, which may affect the study outcome, and which is deemed impossible to discontinue for the duration of the study, primarily AUD medication
5. Insufficient memory of the trauma (assessed using the CAPS-5)
6. Dissociation which is more difficult or affects the subject more than her PTSD
7. Somatic or psychiatric illness where it is deemed to not be in the subject’s best interest to participate in the study
8. IQ < 70

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. PTSD symptom severity will be measured using the Clinician-Administered PTSD Scale (CAPS-5) at baseline, sessions 6 and 12 and six and nine months post baseline.<br> 2. Alcohol consumption per week (grams per week) and heavy drinking days (HDD) will be measured using the Timeline Follow Back (TLFB) at baseline, sessions 6 and 12 and six and nine months post baseline.<br>