MedPath

Evaluation of positive effects of computer-based cognitive therapy in the home context on healthcare supply

Phase 2
Conditions
F06.7
F06.8
F06.9
Mild cognitive disorder
Other specified mental disorders due to brain damage and dysfunction and to physical disease
Unspecified mental disorder due to brain damage and dysfunction and to physical disease
Registration Number
DRKS00026651
Lead Sponsor
HASOMED GmbH
Brief Summary

Sample: A total of 51 subjects with cognitive impairment were included, 3 of whom dropped out of the study due to health or personal problems. The final sample of 48 people (male:29/female19) had an average age of 52.5 (SD 9.2) years and an average time since brain injury of 9.8 months (SD 4.8). The underlying diseases of the study participants were embolic stroke (n=21), traumatic brain injury (n=6), post-Covid syndrome (n=5), cerebral haemorrhage (n=4), multiple sclerosis (n=4), tumour (n=2), inflammatory diseases of the CNS (n=2), other neurological diseases (n=4). Feasability of the training procedure: The training was prescribed by the therapists 3-7 times a week and the content was based on the patient's cognitive profile. Attention training was predominantly prescribed. The majority of patients were able to perform the training without additional help. Few used the technical support. The adherence of the patients was rated as good with an average of 77.20% (SD=13.26) of the prescribed training sessions. On average, 26.75 training sessions were carried out (SD=13.26), which corresponded to an average training duration of 8.98 hours (SD=3.80) within 4 weeks of training. Training effects: The intervention group reported an improved quality of life in the post-test questionnaire, while the control group reported no changes (Friedmann test: L-1 questionnaire, ?2 (1, n = 24) = 5.56, p = 0.018). In addition, significant improvements in well-being were reported in the intervention group (HEALTH-49 B questionnaire, ?2 (1, n = 24) = 4.77, p = 0.029). The intervention group improved significantly compared to the control group in basal responsiveness (TAP Alertness, significant time × condition interaction: F(1,41) = 4.84, p = 0.033, ?²p = 0.11), which can be interpreted as an indication of an increased ability to concentrate. No other significant time x condition interactions were found. There were significant changes in processing speed, divided attention, visual exploration, anterograde memory and logical reasoning in both groups. In the intervention group, improvements in the extent of subjective cognitive impairment were experienced after training (M = 2.91, SD = 0.85, mode = 3 on a 5-point Likert scale), as well as a significant improvement in cognitive symptoms in everyday life (?2 (1, n = 24) = 7.20, p = 0.007).

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
52
Inclusion Criteria

Subjects have cognitive deficits (diagnosis of F06.7 - F06.9, or professional assessment by a clinical neuropsychologist) as a result of a diagnosed acquired brain injury (e.g. stroke).
- Subjects have access to a computer with internet connection (PC or laptop; MAC)
- Test persons are able to operate the PC and training software independently.
- Test persons have sufficient motivation to train cognitive performance with RehaComOnline.
- Test persons are continuously available for training during the intervention period.

Exclusion Criteria

- a one-time damaging event (e.g. stroke, craniocerebral trauma) occurred more than 2 years ago
- Psychological or cognitive limitations that prevent independent training (e.g. severe neglect, aphasic symptoms)
- parallel provision of cognitive therapy as part of neuropsychological, psychotherapeutic or occupational therapy treatment
- Pregnancy or breastfeeding

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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