NCT07212946已完成2 期
Four Doses of Ayahuasca or Esketamine in Major Depressive Disorder: a Double-blind Randomized Trial
干预措施
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Beck Depression Inventory
研究概览
简要总结
Double-blind, randomized trial comparing 4 weekly doses of oral ayahuasca and esketamine in patients with major depression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Clinical diagnosis of depressive disorder
排除标准
- •- Presence of psychiatric and other medical comorbidities
研究组 & 干预措施
ayahuasca
Experimental
oral ayahuasca
干预措施: Ayahuasca (Drug)
ayahuasca
Experimental
oral ayahuasca
干预措施: Esketamine (Drug)
esketamine
Active Comparator
oral esketamine
干预措施: Ayahuasca (Drug)
esketamine
Active Comparator
oral esketamine
干预措施: Esketamine (Drug)
结局指标
主要结局
Beck Depression Inventory
时间窗: 49 days
21-question multiple-choice self-report inventory, where higher scores mean worse/more depressive symptoms
次要结局
未报告次要终点
研究者
Rafael Guimarães dos Santos
PhD
University of Sao Paulo
研究点 (1)
Loading locations...
相似试验
已完成
3 期
A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)Postoperative PainNCT00092339Merck Sharp & Dohme LLC125
已完成
1 期
Comparative Study of Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of Single Intravenous Doses of BCD-148 and Soliris®Healthy SubjectsNCT04027803Biocad78
已完成
2 期
A Study to Evaluate the Efficacy After Allergen Challenge, Safety and Tolerability of Inhaled CHF6001 DPI in AsthmaticsAsthmaNCT01689571Chiesi Farmaceutici S.p.A.36
已完成
不适用
A study comparing mixture of local anaesthetic agents lignocaine and ropivacaine versus sequential lignocaine followed by ropivacaine in patients undergoing surgery on hands and arms under regional anaesthesia.CTRI/2020/03/024013Mridul Dhar66
撤回
2 期
Safety & Efficacy of Intranasal Dexmedetomidine, Fentanyl & Midazolam in the Pediatric Emergency RoomAcute Stress DisorderPainAnxietyNCT05057689Nationwide Children's Hospital180