The protective effect of a nasal steroid (Fluticasone furoate) on exercise induced airway obstruction in cold air.
Phase 4
Withdrawn
- Conditions
- Exercise induced Airway obstructionLaryngeal hyperreactivity10038716
- Registration Number
- NL-OMON31652
- Lead Sponsor
- Medisch Spectrum Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 91
Inclusion Criteria
children (12-17 years) with a history allergic rhinitis and/or allergic asthma
able to perform lung-function
FEV1>70% of predicted
clinically stable for 3 weeks
Exclusion Criteria
Use of nasal/systemic steroids
bronchodilators prior to test
other cardiac or pulmonary disease
signs of gastro-oesophagal reflux
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Cold air exercise provocation test. Lungfunction will be determined with<br /><br>spirometric and oscillometric measurements.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Asthma Controle Questionnaire by Juniper<br /><br>Borg scale of dyspneoa</p><br>