Influence of antimicrobial peptide (alpha defensins; beta defensins) expression in appendicitis acuta - a prospective cross-sectional study.
Not Applicable
- Conditions
- K35Acute appendicitis
- Registration Number
- DRKS00024704
- Lead Sponsor
- niversitätsklinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 147
Inclusion Criteria
Suspected diagnosis on the basis of clinical appearance, blood values and/or image morphology
Exclusion Criteria
- Minority
- Lack of capacity to consent
- Active hepatitis C and HIV
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary endpoint is to determine the expression levels of alpha- and beta-defensins in appendicitis acuta. The determination was performed by means of quantitative real time PCR from the postoperatively obtained appendix vermiformis resectate.
- Secondary Outcome Measures
Name Time Method - Determination of prognostic factors for the <br> Evaluation of the severity of appendicitis acuta<br>