During surgery, blockade of celiac plexus for pain relief in patients having inoperable pancreatic or gastric or gall bladder cancer.
Phase 4
- Conditions
- Health Condition 1: null- Healthy patient fit to undergo surgeryHealth Condition 2: C269- Malignant neoplasm of ill-definedsites within the digestive system
- Registration Number
- CTRI/2018/05/013667
- Lead Sponsor
- All India Institute of Medical Sciences AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
40 patients of American Society of Anesthesiologist (ASA) physical status I, II and III of age group >18 years of either sex admitted at Dr BRA IRCH AIIMS and scheduled to undergo curative surgeries for pancreatic, stomach and gall bladder carcinoma but found unresectable at the time of laparotomy under general anaesthesia
Exclusion Criteria
1. Patient refusal
2. Respiratory insufficiency
3. Haemodynamic instability
4. Abnormal thyroid function
5. Renal or hepatic insufficiency,
6. History of any chronic pain
7. Unstable personality and abuse liability.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the analgesic efficacy of intraoperative celiac plexus neurolysis with pharmacological therapy for management of postoperative pain on day 1, 2 and 3 in patients with unresectable pancreatic, stomach and gall bladder cancer.Timepoint: Postoperative day 1,2 and 3
- Secondary Outcome Measures
Name Time Method Cumulative morphine consumption <br/ ><br>Severity of pain and quality of lifeTimepoint: At 1,3 and 6 months of neurolytic procedure.