Effect of Rubus Occidentalis Extract on Plasma Glucose Levels in Subject With Prediabetes
Phase 4
Completed
- Conditions
- Prediabetes (Impaired Fasting Glucose and/or Impaired Glucose Tolerance)
- Interventions
- Registration Number
- NCT01964703
- Lead Sponsor
- Korea University Anam Hospital
- Brief Summary
The purpose of this study is to determine whether Rubus occidentalis extract could improve fasting or postprandial serum glucose levels, and related metabolic markers among patients with prediabetes (impaired fasting glucose and/or impaired glucose tolerance).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 29
Inclusion Criteria
- 19 years of age or older
- prediabetes (fasting plasma glucose 100-125mg/dl, and/or post 75g OGTT plasma glucose 140-199mg/dl)
Exclusion Criteria
- pregnant women
- taking anti-hyperglycemic agents within 3 months at the time of enrollment
- history of heart failure, myocardial infarction, cerebral infarction
- uncontrolled hypertension (systolic BP > 160mmHg, or diastolic BP > 100mmHg)
- serum triglyceride level > 500mg/dl
- kidney dysfunction (serum Creatinine > 30% of upper normal limits)
- hepatic dysfunction (AST, ALT > 3 times of upper normal limits)
- taking systemic glucocorticoids within 1 month
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Rubus occidentalis extract 900mg Rubus occidentalis extract taking Rubus occidentalis extract 900mg/day for 12weeks Rubus occidentalis extract 1800mg Rubus occidentalis extract taking Rubus occidentalis extract 1800mg/day for 12weeks
- Primary Outcome Measures
Name Time Method serum glucose (fasting and post 75g oral glucose tolerance test) 12 weeks
- Secondary Outcome Measures
Name Time Method serum insulin 12 weeks