Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder
Completed
- Conditions
- Bipolar Disorder
- Registration Number
- NCT02655978
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Brief Summary
The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) or bipolar type II (BDII) compared to matched controls, and to utilize this information to determine if high-frequency deep brain stimulation (DBS) of the rostral dorsal CB has realistic potential as a therapy for producing mood stabilization in patients with BDI or BDII.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Differences in connectivity in the rostral dorsal CB in patients with BDI or or BDII compared to matched controls Day 1 The imaging visit will consist of an MRI with diffusion-weighted imaging (DWI) sequences
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Hospitals Cleveland Medical Center
🇺🇸Cleveland, Ohio, United States
University Hospitals Cleveland Medical Center🇺🇸Cleveland, Ohio, United States