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临床试验/NCT02655978
NCT02655978已完成不适用

Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder

University Hospitals Cleveland Medical Center1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2016年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
45
试验地点
1
主要终点
Differences in connectivity in the rostral dorsal CB in patients with BDI or or BDII compared to matched controls

研究概览

简要总结

The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) or bipolar type II (BDII) compared to matched controls, and to utilize this information to determine if high-frequency deep brain stimulation (DBS) of the rostral dorsal CB has realistic potential as a therapy for producing mood stabilization in patients with BDI or BDII.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Differences in connectivity in the rostral dorsal CB in patients with BDI or or BDII compared to matched controls

时间窗: Day 1

The imaging visit will consist of an MRI with diffusion-weighted imaging (DWI) sequences

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jennifer Sweet, MD

Neurosurgeon

University Hospitals Cleveland Medical Center

研究点 (1)

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