Ocular Response Analyzer Assessment of Intraocular Pressure and Corneal Biomechanical Properties in Myopic and Anisometropic Patients Under Atropine Treatment

• Conditions: Myopia; Anisometropia

• Registration Number: NCT00658502
• Lead Sponsor: Far Eastern Memorial Hospital

Brief Summary

Our study has three parts has three parts, and the main aim of the study is to find out if corneal hysteresis was associated with myopia or even a predictor of myopia poor control predictor:

* Part 1 of our study: patients with anisomeropia whose spherical equivalent refraction as measured by cycloplegic autorefraction between the two eyes differ greater than 1.5 D.

* Part 2 of our study: Minus spherical equivalent refraction as measured by cycloplegic autorefraction.

* Part 3 of our study: patients with minus spherical equivalent refraction as measured by cycloplegic autorefraction who are under regular atropine for the treatment of myopia;patients who are prescribed with atropine treatment are in need of myopia control instead of for research interest

Detailed Description

Not available

Study Timeline

• Status Verified: 2008-03
• Study Start: 2008-03
• Study First Submitted: 2008-04-11
• Study First Submitted QC: 2008-04-14
• Last Update Submitted: 2008-04-14
• Study First Posted: 2008-04-15
• Last Update Posted: 2008-04-15
• Primary Completion: 2009-08
• Study Completion: 2009-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

1. Normal ocular health other than myopia or anisometropia
2. In good general health with no history of prematurity or cardiac or significant respiratory diseases
3. No allergy to atropine, tropicamide, proparacaine, and benzalkonium chloride
4. No previous or current use of contact lenses, bifocals, progressive addition lenses
5. No amblyopia or manifest strabismus, including intermittent tropia

Exclusion Criteria

1. presence of keratoconus or other corneal disease
2. previous eye drops usage except Atropine
3. major ocular surgery history (including refractive surgery, scleral buckle, glaucoma filtering, cornea transplant, cataract and vitreoretinal surgery)
4. presence of other ocular conditions such as glaucoma, uveitis, or other ocular inflammatory or vitreoretinal diseases.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
axial length, corneal hysteresis	3 month

Secondary Outcome Measures

Name	Time	Method
Refractive error, visual acuity, , intraocular pressure, , and corneal thickness	3 month

Trial Locations

Locations (1)

Far Eastern Memorial Hospital; 🇨🇳 Pan-chiao, Taipei county, Taiwan