Inhalation of Low Molecular Weight Heparins as a prophylaxis to prevent SARS-CoV-2 infectio
Completed
- Conditions
- corona virus infectionCOVID-1910047438
- Registration Number
- NL-OMON50776
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 28
Inclusion Criteria
Healthy men and women between ages 18-65 with no medical history of
immunodeficiencies or chronic illness.
Exclusion Criteria
COVID-19 in the volunteers medical history.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Primary endpoint: SARS-CoV-2 binding to the isolated cells will be measured by<br /><br>the SARS-CoV-2 binding assay to obtain a proof of concept that in vivo<br /><br>application of LMWH block virus binding. The amount of total virus bound to<br /><br>epithelial cells will be measured in pg/ml. </p><br>
- Secondary Outcome Measures
Name Time Method