Assessing if apo b levels correlate with the severity of myocardial infarction

Completed

Conditions: Acute myocardial infarction,

Registration Number: CTRI/2021/07/034583

Lead Sponsor: Kasturba medical college Manipal

Brief Summary: Diabetes Mellitus is a major risk factor for cardiovascular diseases and has been associated with 2-4 fold higher mortality. The risk estimation has for long been based on LDL but there is atherogenic dyslipidemia in diabetes which is characterised by low Hdl , elevated triglycerides and LDL . ApoB being present in very low density lipoproteins, intermediate density lipoprotein cholesterol and LDL cholesterol is a better indicator in the assessment of atherogenic dyslipidemia .

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 144

Inclusion Criteria

Type 2 DM patients -First ACS event -Patients who have undergone coronary angiogram.

Exclusion Criteria

Patients with current ACS event ,Type 1DM, Age less than 18 year -Patients with liver cirrhosis,CKD disease ,-viral infections like Hepatitis B,Hepatitis C or HIV, Hyperthyroidism, Familial hypercholesterolemia.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation between severity of coronary artery disease and Apo B levels	1 year

Secondary Outcome Measures

Name	Time	Method
Correlation between apo and LDL levels	1 year

Trial Locations

Locations (1): Kasturba hospital, Manipal
🇮🇳
Udupi, KARNATAKA, India
Kasturba hospital, Manipal
🇮🇳Udupi, KARNATAKA, India
Mukhilan Selvakumar C
Principal investigator
9003877002
mukhilan.c@learner.manipal.edu