Fever-based versus guideline-based antibiotic therapy for acute cholangitis following successful endoscopic biliary drainage: a multicenter randomized trial (FANTASTIC trial)
- Conditions
- Acute cholangitis
- Registration Number
- JPRN-UMIN000019814
- Lead Sponsor
- The University of Tokyo Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 54
Not provided
1. Patients with acute pancreatitis 2. Patients with other active concomitant infections (liver abscess, pneumonia, infective endocarditis, etc.) 3. Patients with undrained bile ducts due to multiple biliary strictures. 4. Patients who have undergone biliary stenting or percutaneous biliary drainage. 5. Patients with previous choledochojejunostomy. 6. Patients who have participated in this study. 7. Patients receiving steroid or immunosuppressive agent. 8. Patients who have antipyretic analgesics or NSAIDs within 24 hrs before the diagnosis of cholangitis. 9. Patients receiving chemotherapy. 10. Patients who have received antibiotics within 2 weeks before the diagnosis of cholangitis. 11. Patients considered ineligible for this study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The recurrence rate of cholangitis within 30 days after withdrawal of antibiotic therapy.
- Secondary Outcome Measures
Name Time Method