Effects of a single session of action-observation-execution and accelerated skill acquisition program on corticospinal excitability and reach to grasp in individuals with subacute stroke

Phase 2

Active, not recruiting

• Conditions: Subacute stroke; Stroke, task- oriented training, hand function, action observation, neural plasticity

• Registration Number: TCTR20190904004
• Lead Sponsor: St.louis college

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-09-04
• Study Completion: 2020-09-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

1) First-time subcortical ischemic or hemorrhagic stroke, 1-6 months after stroke occurred
2)Age 20-80 years old with unilateral stroke
3) Right hand dominant
4) Mild to moderate UE impairment
5) Intact cognitive function
6) Able to sit independently for at least one hour
7) Normal or corrected vision

Exclusion Criteria

1)Severs pain on paretic limb

2)Severe UE sensory impairment
3)Other neurological condition that effected hand function
4)Motor aphasia, sensory aphasia and global aphasia
5)Receive other task specific training of UE
6)Positive screening for contraindication of TMS

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cortico-spinal excitability and RTG kinematics Baseline, Post training immediately, follow up at 1 week Transcranial magnetic stimulation and electromagnetic tracking system

Secondary Outcome Measures

Name	Time	Method
SIS score, Motivation assessment, Grip strength test Baseline, Post training immediately, follow up at 1 week Questionnaire and hand dynamometer