Effectiveness of Exercise Applications on Hepatic Steatosis and Physical Fitness in Patients With NAFLD

Not Applicable

Completed

• Conditions: Nonalcoholic Fatty Liver Disease

• Registration Number: NCT03461562
• Lead Sponsor: Okan University

Brief Summary

Purpose of the study will investigate the effects of two different training programs on hepatic steatosis and physical fitness parameters. This trial is designed in a randomized controlled study plan and aerobic training (40 minutes) wil be combined with Whole Body Vibration Training (WBVT for 15 minutes) which is made up of a shorter time application. WBVT to be applied instead of the resistance exercises.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-05
• Study First Submitted: 2018-02-27
• Study First Submitted QC: 2018-03-08
• Study First Posted: 2018-03-12
• Primary Completion: 2018-06-30
• Status Verified: 2018-08
• Study Completion: 2018-08-01
• Last Update Submitted: 2018-08-03
• Last Update Posted: 2018-08-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• Clinical diagnosis of NAFLD
• Age range of 18-65 years
• Participants who are not in an active exercise program
• Participants who are not on an active diet program

Exclusion Criteria

• Pregnancy
• Chronic inflammatory process
• Rheumatic disease
• Cognitive disorders
• Obstacles to achieve physical performance tests
• Presence of other conditions that may cause liver steatosis
• Inability to do WBVT or Aerobic Exercises

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
FibroScan	8 weeks	İn the Fibroscan measurement session, the patient lying supine, the tip of the transducer is placed on the skin between the ribs over the right lobe of the liver. At least 10 validated measurements with a ratio of interquartile range (IQR) and median LSM of less than or equal to 30 percent are required for an interpretation of significant fibrosis or cirrhosis.

Secondary Outcome Measures

Name	Time	Method
Profile of liver enzymes	8 weeks	Serum liver enzymes ALT, AST, GGT, ALP will be recorded.

Trial Locations

Locations (1)

Marmara University; 🇹🇷 Istanbul, Turkey