Effect of Intravenous Lignocaine, Dexmedetomidine and their combination on pulse,blood pressure and oxygen saturation during operation, pain after operation and quality of recovery in patients undergoing uterus removal operation by robot

Completed

• Conditions: Other specified menopausal and perimenopausal disorders,

• Registration Number: CTRI/2019/09/021323
• Lead Sponsor: AIIMS RISHIKESH

Brief Summary

This study is an interventional, single blinded, randomized controlled trial comparing the effect of intravenous  Lignocaine, Dexmedetomidine and their combination on itraoperative haemodynamics, postoperative pain and Quality of recovery in patients undergoing Robotic Abdominal Hysterectomy, to be conducted in AIIMS Rishikesh, India over an expected duration 8 months. The primary outcome is to assess postoperative pain as measured by VAS at 4 hours postoperatively The secondary outcome are Time to first bowel sounds and flatus, Intraoperative consumption of propofol, fentanyl, and vecuronium, Post operative fentanyl requirement and QoR15 score on day 1,2 and on the day of discharge.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-10
• Study Completion: 2020-03-13
• Last Update Posted: 2021-08-17

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

1.Female patients aged 30-65 years, 2.ASA grade I & II 3.Patients undergoing elective Robotic Abdominal Hysterectomy under general anaesthesia will be selected.

Exclusion Criteria

1.ASA grade III & IV patients 2.Age >65 years 3.BMI>35kg/m2 4.Allergy to local anaesthetic agents 5.History of use of opioid, analgesics and psychotropic drugs and beta blockers, substance abuse preoperatively 6.Uncontrolled hypertension, A-V conduction block, history of sleep apnoea.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess post operative pain as measured by VAS	4 hours after surgery

Secondary Outcome Measures

Name	Time	Method
1.Time to first bowel sounds and flatus	2.Intraoperative consumption of propofol, fentanyl and vecuronium

Trial Locations

Locations (1)

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RISHIKESH; 🇮🇳 Dehradun, UTTARANCHAL, India

ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RISHIKESH

🇮🇳Dehradun, UTTARANCHAL, India

Dr PUDI SIVAJI

Principal investigator

9177662720

sivajipudi717@gmail.com