A clinical trial to study the effect of adding dexmedetomidine to ropivacaine scalp block to attenuate the hemodynamic response to skull pin placement in neurosurgical procedures
Phase 1
- Conditions
- Health Condition 1: - Health Condition 2: C71- Malignant neoplasm of brain
- Registration Number
- CTRI/2019/08/020826
- Lead Sponsor
- Department Of Anesthesiology and Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients of either sex
Patients aged 18 to 65 years
American Society of Anesthesiologists physical status grade I and II
Patients scheduled for elective neurosurgical procedures under general anesthesia with tracheal intubation
Exclusion Criteria
Patients with uncontrolled hypertension
Patients with preoperative bradycardia, ischemic heart disease, cardiac arrhythmias
Patients with severe hepatic and renal disease
Patients with past history of craniotomy
Patients allergic to study drugs
Patients on alpha blockers treatment preoperatively
Patient refusal
Patient unable to give consent
Pregnant women and lactating mothers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure are measured at different time points following skull pin placement .Timepoint: Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure are measured at 1 3 5 10 minutes following skull pin placement
- Secondary Outcome Measures
Name Time Method 2.Number of episodes of hypertension, hypotension, bradycardia and tachycardiaTimepoint: during study period.