The Effect of Long-pulsed 1064 nm nd: Yag Laser-assisted Hair Removal on Some Skin Flora and Pathogens: an in Vivo Study
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- to compare changes in bacterial count and composition of axillary flora after laser hair removal
研究概览
简要总结
- To evaluate the effect of ND-YAG laser hair removal on some skin flora and pathogens: an in vivo study.
- To determine the immediate and long term effect of ND-YAG laser on total viable bacterial count, some skin flora and pathogens of laser-assisted hair removal in axilla.
- To assess the relation between this effect and bromohidrosis.
详细描述
This Quasi-experimental interrupted time series study will be conducted on 30 female participants who will be recruited from the Dermatology Outpatient Clinic of the Alexandria Main University Hospital.
Four sessions of laser assisted hair removal at 4 weeks intervals (S1, S2, S3 and S4) using long pulsed ND: YAG (Cynosure Elite+™, Westford, USA). The following parameters will be used according to the nature of hair (1064 nm, 15-18 mm spot size, fluence of 24-35 J/cm2, pulse duration 30-40 ms).
- Swabs will be collected immediately and after each session
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •No previous laser hair removal sessions involving axilla. Fitzpatrick skin type III-VI.
排除标准
- •Skin diseases such as atopic dermatitis, psoriasis, fungal or herpetic infections.
- •Systemic diseases such as diabetes or endocrinal dysfunction.
- •Patients receiving immunosuppressive therapy.
- •Pregnant or lactating females.
结局指标
主要结局
to compare changes in bacterial count and composition of axillary flora after laser hair removal
时间窗: 4 month
counting bacterial colonies (aerobic,anaerobic,lipophyllic and staphylococcal) using colony counter
次要结局
- To assess the relation between this effect and bromohidrosis.(4 month)
- To determine the immediate and long term effect of ND-YAG laser on total viable bacterial count, some skin flora and pathogens of laser-assisted hair removal in axilla(4 month)
研究者
marwa eldeeb
lecturer of dermatology
Alexandria University