A Novel Scoring System for Predicting the Success of Percutaneous Coronary Interventions in Patients With Chronic Total Occlusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 493
- 试验地点
- 1
- 主要终点
- PCI technical success
研究概览
简要总结
The investigators conducted a retrospective, single-center observational registry upon which one novel scoring system was formed and evaluated for their accuracy in predicting technical success. The investigators reviewed the clinical and angiographic records of 432 patients with 459 CTO lesions who underwent percutaneous recanalization attempts recruited between January 2012 and November 2023. The investigators aims to develop and validate a novel scoring system for predicting CTO-PCI success.
详细描述
Chronic total occlusions (CTO) accounting for about 15-20% of coronary artery lesions can be challenging and only 10-15% of patients undergo successful percutaneous coronary intervention (PCI) .Thanks to the technological and device advances, the marked improvement of PCI success rates could be seen. However, in contrast to non-CTO lesions, these procedures are accompanied by longer procedure time, contrast and radiation burden, and higher complication rates. The possibility to predict which CTOs are more likely to be treated successfully is still of utmost importance for patient selection. Several scores have been proposed to predict the procedural success rate, such as J-CTO, CL-Score, Progress-Score et al , J-CTO is widely accepted. But Karatasakis et al.showed that these scores performed moderately in predicting technical outcome, while ignoring many factors such as stumpless lesion which may exert an influence on the procedural success. The investigators aims to develop and validate a novel scoring system for predicting CTO-PCI success.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •complete occlusion of the coronary artery, confirmed by coronary angiography with TIMI flow grade 0, and occlusion for ≥3 months;
- •presence of angina or angina-equivalent symptoms ; undergo coronary intervention;
排除标准
- 未提供
结局指标
主要结局
PCI technical success
时间窗: immediately after PCI
Technical success of CTO PCI was defined as successful revascularization with \<30% residual diameter stenosis and restoration of antegrade TIMI flow grade 3 of \<30% residual diameter stenosis within the treated segment and restoration of antegrade TIMI flow grade 3.
次要结局
未报告次要终点
研究者
Chunjian Li
Director of Cardiology
The First Affiliated Hospital with Nanjing Medical University
