跳至主要内容
临床试验/NCT06322914
NCT06322914已完成不适用

A Novel Scoring System for Predicting the Success of Percutaneous Coronary Interventions in Patients With Chronic Total Occlusion

The First Affiliated Hospital with Nanjing Medical University1 个研究点 分布在 1 个国家目标入组 493 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
493
试验地点
1
主要终点
PCI technical success

研究概览

简要总结

The investigators conducted a retrospective, single-center observational registry upon which one novel scoring system was formed and evaluated for their accuracy in predicting technical success. The investigators reviewed the clinical and angiographic records of 432 patients with 459 CTO lesions who underwent percutaneous recanalization attempts recruited between January 2012 and November 2023. The investigators aims to develop and validate a novel scoring system for predicting CTO-PCI success.

详细描述

Chronic total occlusions (CTO) accounting for about 15-20% of coronary artery lesions can be challenging and only 10-15% of patients undergo successful percutaneous coronary intervention (PCI) .Thanks to the technological and device advances, the marked improvement of PCI success rates could be seen. However, in contrast to non-CTO lesions, these procedures are accompanied by longer procedure time, contrast and radiation burden, and higher complication rates. The possibility to predict which CTOs are more likely to be treated successfully is still of utmost importance for patient selection. Several scores have been proposed to predict the procedural success rate, such as J-CTO, CL-Score, Progress-Score et al , J-CTO is widely accepted. But Karatasakis et al.showed that these scores performed moderately in predicting technical outcome, while ignoring many factors such as stumpless lesion which may exert an influence on the procedural success. The investigators aims to develop and validate a novel scoring system for predicting CTO-PCI success.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • complete occlusion of the coronary artery, confirmed by coronary angiography with TIMI flow grade 0, and occlusion for ≥3 months;
  • presence of angina or angina-equivalent symptoms ; undergo coronary intervention;

排除标准

  • 未提供

结局指标

主要结局

PCI technical success

时间窗: immediately after PCI

Technical success of CTO PCI was defined as successful revascularization with \<30% residual diameter stenosis and restoration of antegrade TIMI flow grade 3 of \<30% residual diameter stenosis within the treated segment and restoration of antegrade TIMI flow grade 3.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Chunjian Li

Director of Cardiology

The First Affiliated Hospital with Nanjing Medical University

研究点 (1)

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