Investigating the predictability of postoperative pain by intraoperative nociception monitoring and EEG

Recruiting

• Conditions: R52.0; R52.2; F05.8; Acute pain; Other chronic pain; Other delirium

• Registration Number: DRKS00033159
• Lead Sponsor: Klinik für Anästhesie, Intensiv-, Notfall- und Schmerzmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

2. patients with an ASA status I to III (according to the American Society of Anesthesiologists)
3. planned elective surgery under total intravenous general anesthesia (TIVA)
4. planned securing of the airway by tracheal intubation
5. ability to give written informed consent
6. presence of written informed consent

Exclusion Criteria

1. required rapid sequence induction
2. taking antipsychotics and antidepressants
3. chronic pain disorder with current opioid medication
4. inability to answer the preoperative questionnaire unaided
5. pre-existing pupillary anomaly or condition after pupil-altering eye surgery
6. BMI >35 kg/m2

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. chronic postoperative pain

Secondary Outcome Measures

Name	Time	Method
2. acute postoperative pain<br>3. postoperative consumption of painkillers<br>4. postoperative delirium<br>5. postoperative increase of stress hormones in the blood<br>6. clinical responses to nociceptive and non-nociceptive stimulation during induction of anesthesia<br>7. clinical responses to nociceptive and non-nociceptive stimulation during anesthesia maintenance <br>8. clinical responses to nociceptive and non-nociceptive stimulation during emergence from anesthesia