Effect of pregabalin on Total knee replacement post operative pai

Phase 3

Recruiting

• Conditions: postoperative Pain; Total knee replacement; Anaesthesiology - Pain management

• Registration Number: ACTRN12623001360606
• Lead Sponsor: Bahrain defence forces hospital, royal medical services

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-12-21
• Last Update Posted: 8 January 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1.Age between 21 to 85 year
2.Elective Regional anesthesia.
3.Able to follow study protocol

Exclusion Criteria

1.ASA -IV
2.Age <18 & > 85 years
3.Patients on pregabalin for chronic neuropathic pain.
4.Patient under General anesthesia
5.Patients with chronic liver failure
6.Patients with chronic renal failure on Hemodialysis
7.Patients on opioid (>3 month)
8.Patient with complicated knee surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To measure Total Knee replacement Postoperative Pain by Visual Analogue Score 0-10[ Postoperative at 4hrs, 8hrs, 12hrs, 24hrs, 36 hrs, 48hrs, 60hrs, and 72hrs.]

Secondary Outcome Measures

Name	Time	Method
Sedation score[ Sedation score: RASS score postoperative at 4hrs, 8hrs, 12hrs, 24hrs, 36 hrs, 48hrs, 60hrs, 72hrs. <br>];Total Opioids consumption at 72 hrs<br>assessed from medical records of OPIODS Consumption, kept by nursing staff. [ post operative 72 hrs];Patient satisfaction at 72 hrs : rated as numeric 1-5 (1=not satisfied, 5=fully satisfied)<br>[ Postoperative 72 Hrs]