ISRCTN30294119已完成未知
A pragmatic randomised controlled trial comparing the effectiveness and cost effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of Standard And New Antiepileptic Drugs (SANAD-II)
niversity of Liverpool (UK)0 个研究点目标入组 1,510 人开始时间: 2012年7月3日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 1,510
研究概览
简要总结
2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/32847927/ protocol (added 02/09/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33838757/ results for newly diagnosed focal epilepsy (added 13/04/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33838758/ results for newly diagnosed generalised and unclassifiable epilepsy (added 13/04/2021) 2021 Other publications in https://pubmed.ncbi.nlm.nih.gov/34225782/ sub study on methods (added 07/07/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34931602/ HTA report (added 22/12/2021)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Male and female aged 5 years or older
- •2. Two or more spontaneous seizures that require antiepileptic drug treatment
- •3. Untreated and not previously treated with antiepileptic drugs
- •4. Antiepileptic drug monotherapy considered the most appropriate option
- •5. Willing to provide consent (patients parent/legal representative willing to give consent where the patient is aged under 16 years of age)
排除标准
- •1. Provoked seizures (e.g. alcohol)
- •2. Acute symptomatic seizures (e.g. acute brain haemorrhage or brain injury)
- •3. Currently treated with antiepileptic drugs
- •4. Progressive neurological disease (e.g. known brain tumour)
研究者
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