eukapheresis of healthy volunteer donors for T cell study and TolDC production process validations
- Conditions
- Hematological and immunological diseases1001884910027665
- Registration Number
- NL-OMON52474
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
-Age > 17 years
-Able to comprehend and give signed informed consent
Exclusion Criteria
-Any concurrent systemic comorbidity
-Symptoms of infectious disease in the 3 weeks prior to donation
-Vaccination of any kind in the 3 weeks prior to donation
-Requirement for additional infectious disease screening
-Insufficient vascular access for the purpose of the apheresis procedure
-Pregnancy
-Any condition that in the opinion of the IHB medical team might interfere with
the safe completion of an apheresis procedure
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Successful collection of sufficient numbers of MNC for T cell or monocyte<br /><br>isolation for the purpose of testruns and validation procedures for T cell or<br /><br>tolerogenic dendritic cell studies.</p><br>
- Secondary Outcome Measures
Name Time Method <p>None</p><br>