Serological investigations of blood donors from the city and area around Magdeburg for antibodies against SARS-CoV-2 (COVID-19)
Recruiting
- Conditions
- Serological testing of antibodies against SARS-CoV-2 and an analysis of differences between symptomatic and asymptomatic COVID19 courses.
- Registration Number
- DRKS00023263
- Lead Sponsor
- Institut für Medizinische Mikrobiologie und Krankenhaushygiene (IMMB)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 4500
Inclusion Criteria
18 years and interest in blood donation.
Exclusion Criteria
The exclusion criteria are based on the German Medical Association’s donor exclusion criteria
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The frequency of IgG antibodies against SARS-CoV-2 in blood donors will be determined by serological analysis of blood samples over a period of approximately 18 - 21 months and the development over this period will be monitored. <br><br>Measurement period: <br>BP-0: approximately 2,000 available samples from 2019 period.<br>BP-1: approx. 2,000 donors, period: January 21, 2021 to April 30, 2021<br>BP-2: approx. 2,000 donors, period: July 01 to October 31, 2021<br>BP-3: approx. 2,000 donors, period: January 24, 2022 to April 30, 2022<br>BP-4: approx. 2,000 donors, period: July 1, 2022 to October 31 2022<br><br>Measurement method: Serological examination by blood collection.
- Secondary Outcome Measures
Name Time Method To examine the influence of age, gender, occupational activities, home conditions, and frequency of family and other social contacts on the frequency of SARS-CoV2 antibodies.<br><br>To analyze differences between participants* with symptomatic and asymptomatic COVID19 histories <br><br>To survey vaccination readiness, vaccination attitudes, and the effect of a vaccination campaign on them, if applicable <br><br>To analyze the impact of vaccines on antibody detection rates.<br><br>The comparison of different antibody tests (test quality).<br><br>Measurement methods: Questionnaires and blood samples.