The Comparative study of effects of Volume Control Ventilation and Manual Ventilation on the Airway Dynamics during induction of General Anaesthesia : A Prospective Randomised Control Study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare Peak Airway Pressure between Volume Control Ventilation and Manual Ventilation during induction of anaesthesia.
研究概览
简要总结
Facemask ventilation plays a crucial role in airway management, serving as
a routine procedure to guarantee sufficient oxygenation until the patient’s
airway can be securely established during the induction of anaesthesia.
Facemask ventilation carries potential risks, including inadequate alveolar
ventilation and gastric insufflation. Retention of carbon dioxide due to
inadequate ventilation causes acidosis which may lead to hypoxemia,
atelectasis, and inadequate depth of anaesthesia. Gastric insufflation (GI)
can cause gastric regurgitation, leading to aspiration.
One of the approaches to make mask ventilation safer in an unprotected
airway is to limit Peak Airway Pressure (PAP).
The entry of air into the stomach during positive pressure facemask
ventilation depends on the peak airway pressure, which is determined by a combination of variables related to the patient’s airway, lung condition, and facemask ventilation.
The relationship between PAP and lower oesophageal sphincter muscle tone is an important factor that can influence the entry of air into the stomach during facemask ventilation which might result in regurgitation and
subsequent pulmonary aspiration.
Manual ventilation (MV) is a commonly used facemask ventilation
technique during the induction of anaesthesia. The adjustable pressure
limiting valve (APL) is preferably set at < 20 cm H2O during MV in adults
in order to prevent Gastric Insufflation.
Thus, this study will compare the effects of Volume Control
Ventilation and Manual Ventilation on the airway dynamics such
as Peak Airway Pressure and End Tidal CO2, during induction of
general anaesthesia. In addition, incidence of Gastric Insufflation
between Volume Control Ventilation and Manual Ventilation,
during induction of general anaesthesia will also be studied.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients of age group 18 to 60 years, undergoing elective surgeries under general anaesthesia, from different departments.
- •Patients classified under American Society of Anaesthesiologists (ASA) 1 and 2 after thorough Pre- Anaesthetic evaluation.
排除标准
- •Patient refusal 2)Pregnant women 3)Patients with BMI of 30kg/m2 and more 4)Patients undergoing emergency surgeries 5)Patients with anticipated difficult airway Mallampatti Grade 3 or 4, short neck.
- •Patients with compromised Respiratory conditions.
- •Patients with Oropharyngeal or Facial Pathologies 8)Patients who are active smokers.
结局指标
主要结局
To compare Peak Airway Pressure between Volume Control Ventilation and Manual Ventilation during induction of anaesthesia.
时间窗: 0 seconds, 30 seconds, 60 seconds, 90 seconds, 120 seconds, 150 seconds, 180 seconds
次要结局
- 1)To compare End Tidal CO2 between Volume Control Ventilation and Manual Ventilation during induction of anaesthesia.(2)To assess the Incidence of Gastric Insufflation between Volume Control Ventilation and Manual Ventilation during induction of anaesthesia.)
研究者
Dr G K ANKUSH
Rajarajeswari Medical College And Hospital , Bangalore