EUCTR2021-002011-61-NL进行中（未招募）1 期
The glutamate/GABA balance as novel therapeutic target for psychotic and cognitive symptoms in 22q11.2 deletion syndrome - Riluzole in 22q11.2DS
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Confirmed diagnosis of 22q11.2 deletion syndrome established by FISH, microarray or MLPA analysis.
- •16 year or older of age and mentally competent (determined by an experienced physician) to give informed consent.
- •Presence of psychotic and/or cognitive symptoms (defined as a score of =4, moderately ill, on the Clinical Global Impression-Schizophrenia Scale (CGI-SCH)).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 45
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Other chromosomal abnormalities.
- •- Current substance abuse / dependence.
- •- Use of first-generation antipsychotics or clozapine.
- •- Contraindications for MRI.
- •- Contraindications for riluzole.
- •- Pregnancy.
研究者
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