Dietary Interventions for Muscle Mass
- Conditions
- Aging
- Interventions
- Other: Intact or minced beef meat
- Registration Number
- NCT01145131
- Lead Sponsor
- Maastricht University Medical Center
- Brief Summary
Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 12
- Non-obese male subjects (BMI<30) between the age of 65-85 years.
- Type II diabetes or other known diseases, use of medication, female, other ages or BMI than indicated above, participation in any regular exercise program.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Beef steak Intact or minced beef meat - Minced beef Intact or minced beef meat -
- Primary Outcome Measures
Name Time Method Muscle protein synthesis 6 h postprandial period Muscle protein synthesis will be expressed as fractional synthetic rate (FSR) by dividing the increment in enrichment in the product, i.e. protein-bound D5phe tracer, by the enrichment of the precursor (=plasma availability).
- Secondary Outcome Measures
Name Time Method Dietary amino acid plasma availability 6h postprandial period The exogenous rate of phenylalanine appearance will be used to assess the bio-availability of dietary-protein derived amino acids in the circulation during the 6h postprandial period following meat intake
Trial Locations
- Locations (1)
Universiteit Maastricht, Bewegingswetenschappen
🇳🇱Maastricht, Limburg, Netherlands