Serum profiles of paracetamol and glutathione after high doses of paracetamol for 6 days
- Conditions
- Healthy volunteers
- Registration Number
- EUCTR2007-000627-17-IS
- Lead Sponsor
- niversity of Iceland
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
Healthy, age 18-60 years.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
History of liver or kidney diseases, history of alcohol abuse, chronic drug use, allergy for paracetamol.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Secondary Objective: To study the possible changes in the blood concentration of glutathione.;Primary end point(s): Blood concentrations of paracetamol snd glutathione. Pharmacokinetic parameters for paracetamol. ;Main Objective: To describe the pharmacokinetics after large doses for 6 days.
- Secondary Outcome Measures
Name Time Method