Effect of paracetamol, low dose Ketamin, paracetamol, NSaid and dexametason on pain and opioid requirements in patients scheduled for primary total hip replacement
- Conditions
- Patient scheduled for primary total hip replacement need postoperativ pain treatment. Morphine has side-effects: nause, vomiting, sedation and dizziness. These sideeffects are of course unpleasent for the patient and sometimes prolongs there stay in the hospital.
- Registration Number
- EUCTR2005-002517-20-DK
- Lead Sponsor
- Dept. of Anaestesiology, University hospital in Glostrup
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
- Patients scheduled for a total hip replacement
- age between 55 and 85
- given there imformed concent
- ASA 1-3
- BMI between 18 and 35
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
Patients who
- are unable to cooperate
- does not speak and understand danish
- has allergy for the drugs used in the trial
- drug or alkohol abuse
- epilepsi
- medecaly treated diabetes
- know kidney disease
- daily use of analgesia - apart from NSAID, COX2 and paracetamol
- treatment with anitidepressive
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method