Comparative cefixime and levofloxacin on infections after urinary tract dilatatio
Phase 3
- Conditions
- rethral Stricture.Urethral stricture, unspecifiedN35.9
- Registration Number
- IRCT20220711055433N2
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 50
Inclusion Criteria
Single urethral stricture and stricture length less than 2 cm
Strictures shorter than 1.5 cm in the anterior urethra
Age older than 18 years old
Exclusion Criteria
Patient refusal of participation
History of allergy to levofloxacin and cefixime
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rinary tract infections after urethral dilatation. Timepoint: The rate of improvement in urinary tract infection in the first, second and third months after dilatation. Method of measurement: The use of Urine analysis and Urine culture.
- Secondary Outcome Measures
Name Time Method Side effects caused by cefixime or levofloxacin. Timepoint: 72 hours after urethral dilatation. Method of measurement: Medical records.
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie cefixime and levofloxacin's efficacy in preventing post-dilatation infections in urethral stricture patients?
How does the comparative effectiveness of cefixime versus levofloxacin in preventing infections after urinary tract dilatation compare to standard-of-care antibiotics in recurrent stenosis management?
Are there specific biomarkers that can predict patient response to cefixime or levofloxacin in the context of urethral stricture recurrence prevention?
What are the known or potential adverse events associated with cefixime and levofloxacin use in post-dilatation settings, and how can they be managed effectively?
What are the current trends in antibiotic use for recurrent urethral stricture infections, and how do cefixime and levofloxacin fit into this therapeutic landscape?