Evaluation of dimensional changes in the alveolar ridge following tooth extraction with and without using decalcified freeze dried bone allograft - A clinical study
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Post-extraction horizontal and vertical dimension of the alveolar ridge as measured from a pre-determined reference point may be influenced with the intervention i.e. addition of bone graft
研究概览
简要总结
Background:
Post-extraction alveolar bone resorption renders the ridge inadequate for the placement of prosthetically driven implants and pontics which in turn leads to unsatisfactory aesthetics or function of the prosthesis. The present clinical trial is an endeavour to investigate the role of bone grafts in mitigating the effects of resorption and allowing successful rehabilitation.
Aim:
1. To investigate the possibility of using bone graft for the formation of functional alveolar bone.
2. To evaluate if implant placement is possible after bone grafting
Methodology:
Forty subjects requiring extraction for teeth with poor prognosis will be included in the randomised controlled clinical trial. Extraction will be performed a-traumatically and ridge measurements taken using a pre-fabricated stent. A re-entry procedure will be undertaken 6 months later for implant placement. Clinical and Ridge parameters will be re-recorded, tabulated and statistically analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients having teeth with poor prognosis that require extraction.
排除标准
- •Patients with systemic diseases (eg: uncontrolled diabetes, hypertension) which contraindicate surgery Pregnant and lactating mothers or those planning a pregnancy Smokers Patients with bleeding disorders.
- •Patients suffering from allergic conditions or history of allergies.
- •Patients on long term systemic antibiotics or non-steroidal anti-inflammatory drugs.
结局指标
主要结局
Post-extraction horizontal and vertical dimension of the alveolar ridge as measured from a pre-determined reference point may be influenced with the intervention i.e. addition of bone graft
时间窗: Ridge Parameters will be assessed at baseline following extraction and then 6 months later at the time of implant placement
次要结局
- NA(NA)