Strength Training Regimen for Normal Weight Diabetics
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Diabetes Mellitus
- Sponsor
- Stanford University
- Enrollment
- 289
- Locations
- 1
- Primary Endpoint
- Change in Hemoglobin A1c across study visits
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The Strength Training Regimen in Normal Weight Diabetics (STRONG-D) study will examine the effectiveness of different exercise regimen types in controlling diabetes for the normal weight type 2 diabetes population.
Detailed Description
In the STRONG-D study, participants are randomly assigned to strength training, aerobic training or a combined strength and aerobic training group. Participants in the exercise group will attend exercise sessions over the course of 9 months at the YMCA. Participants will have opportunities to engage in other activities such as educational run-in visits that will allow for measurement of hemoglobin A1c and emphasize the importance of exercise in improving Type 2 diabetes.
Investigators
Latha Palaniappan, MD, MS
Professor
Stanford University
Eligibility Criteria
Inclusion Criteria
- •Recent hemoglobin A1c result between 6.5%-13%
- •Diagnosis of Type 2 Diabetes Mellitus
- •BMI between 18.5 -25 kg/m2
- •Blood pressure \< 160/100
- •Sedentary lifestyle
- •Able and willing to enroll and meet requirements of the study
Exclusion Criteria
- •Age less than 30 years or greater than 75 years
- •Type 1 diabetes or use of insulin pump
- •Triglycerides \>500 mg/dL
- •Use of weight loss medication
- •Bariatric surgery
- •Consumes \>14 alcoholic drinks per week
- •Pregnancy
- •Plans to be away for more than four weeks
- •Medical conditions which would prevent long-term participation or which would contraindicate physical activity
Outcomes
Primary Outcomes
Change in Hemoglobin A1c across study visits
Time Frame: Baseline, monthly (for 9 months), 9-Months
Secondary Outcomes
- Changes in cardiorespiratory fitness, as measured by 6-minute walk test(Baseline, 9-Months)
- Change in quality of life(Baseline, 9-Months)
- Change in body composition across study visits, as measured using DEXA(Baseline, 9-Months)
- Change in body weight across study visits(Baseline, 9-Months)
- Change in waist circumference across study visits(Baseline, 9-Months)
- Change in blood pressure across study visits(Baseline, 9-Months)
- Change in muscle strength and endurance, as measured by Biodex strength testing(Baseline, 9-Months)
- Change in Dietary Intake, as measured by Food Frequency Questionnaire(Baseline, 9-Months)