Reorganising language after left-hemisphere stroke through right-hemisphere recruitment: an exploratory study - ReorgLang

Radboud Universiteit Nijmegen0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年7月22日

适应症

试验速览

暂无简介。

•* Between 18 * 78 years of age
•* Ischemic or hemorrhagic cerebral infarction of the left hemisphere
•* Postonset of > 6 months (chronic stage)
•* Native speaker of Dutch
•* Pre-morbidly right handed
•* Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.

•* History of previous stroke
•* Pre-existent cognitive problems
•* Severe aphasia (unable to understand instructions or provide consent). This will be operationalised via scores of the Comprehensive Aphasia Test (CAT-NL) or Aachen Aphasia Test (AAT) or Token Test, which are acquired as part of the standard clinical procedure by the co-investigating sites. The following cut-off scores will be used:
•o CAT-NL, part *Mondeling taalbegrip: zinnen*: C-score >= 5, percentile >= 41 (corresponding to average)
•o AAT, part *TB-1 Auditief woordbegrip* and *TB-2 Auditief zinsbegrip*: raw score >= 39, corresponding to C-score >= 5, percentile >= 41
•o Token Test: raw score >= 37, corresponding to percentile >= 41
•* Use of psychotropic medication or recreational drugs
•* Pregnancy
•* Serious head trauma
•* Neurological or psychiatric disorders (other than stroke or epilepsy as a consequence of the stroke)
•* Intractable epilepsy
•* Large or ferromagnetic metal parts in the head (except for a dental wire)
•* Implanted cardiac pacemaker or neurostimulator
•* Somatic symptom and related disorders

发起方