Reorganising language after left-hemisphere stroke through right-hemisphere recruitment: an exploratory study

Completed

• Conditions: Afasie en Taalstoornissen in het kader van hersenletsel; CVA; stroke; 10042258

• Registration Number: NL-OMON47133
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 22 July 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

* Between 18 * 78 years of age
* Ischemic or hemorrhagic cerebral infarction of the left hemisphere
* Postonset of > 6 months (chronic stage)
* Native speaker of Dutch
* Pre-morbidly right handed
* Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.

Exclusion Criteria

* History of previous stroke
* Pre-existent cognitive problems
* Severe aphasia (unable to understand instructions or provide consent). This will be operationalised via scores of the Comprehensive Aphasia Test (CAT-NL) or Aachen Aphasia Test (AAT) or Token Test, which are acquired as part of the standard clinical procedure by the co-investigating sites. The following cut-off scores will be used:
o CAT-NL, part *Mondeling taalbegrip: zinnen*: C-score >= 5, percentile >= 41 (corresponding to average)
o AAT, part *TB-1 Auditief woordbegrip* and *TB-2 Auditief zinsbegrip*: raw score >= 39, corresponding to C-score >= 5, percentile >= 41
o Token Test: raw score >= 37, corresponding to percentile >= 41
* Use of psychotropic medication or recreational drugs
* Pregnancy
* Serious head trauma
* Neurological or psychiatric disorders (other than stroke or epilepsy as a consequence of the stroke)
* Intractable epilepsy
* Large or ferromagnetic metal parts in the head (except for a dental wire)
* Implanted cardiac pacemaker or neurostimulator
* Somatic symptom and related disorders

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified