Effect of Bee Food Supplement Propolis on Food intake, Severity of disease and Quality of life in Patients with Irritable Bowel Syndrome (based on RomeIV criteria): a Randomized Double-Blind Clinical Trial
- Conditions
- Irritable Bowel Syndrome.Irritable bowel syndrome
- Registration Number
- IRCT20190708044154N1
- Lead Sponsor
- Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Patients diagnose irritable bowel syndrome with Rome IV criteria
Filling out the written consent form
Not having allergy to bee products
Pregnant or lactating women
Cases of malignancy or other chronic digestive diseases such as inflammatory bowel disease and celiac disease
Regular use of drugs that modify gastrointestinal movements such as metoclopramide, cisapride, narcotics, diphenoxylate, etc.
Regular use of laxatives
History of major surgery in the digestive system (including Billroth's operating, having any Ostomy and resection of any part of the digestive tract).
Following diet plans
Individuals with daily and regular use of Prebiotic/ probiotic compounds
Consumption antibiotics
People who use psychotherapeutic drugs, including depression and anxiety.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of Irritable bowel syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: IBS Severity Index(IBSSI).
- Secondary Outcome Measures
Name Time Method Quality of life in Patients with Irritable Bowel Syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: Irritable Bowel Syndrome Quality of Life questionnaire (IBS-QOL).;Food intake in Patients with Irritable Bowel Syndrome. Timepoint: At the beginning of the study and the sixth week of the intervention. Method of measurement: 3-Day Food Intake Record.