Biobank For MS And Other Demyelinating Diseases

Active, not recruiting

• Conditions: Transverse Myelitis; Optic Neuritis; Multiple Sclerosis; Neuromyelitis Optica; Acute Disseminated Encephalomyelitis

• Registration Number: NCT00445367
• Lead Sponsor: Accelerated Cure Project for Multiple Sclerosis

Brief Summary

To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-05
• Study First Submitted: 2007-03-08
• Study First Submitted QC: 2007-03-08
• Study First Posted: 2007-03-09
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-18
• Last Update Posted: 2024-04-19
• Primary Completion: 2026-10
• Study Completion: 2036-10

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 3226

Inclusion Criteria

• age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent
• willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture
• experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON

Exclusion Criteria

• history of blood borne pathogens
• allogeneic bone marrow transplant
• clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON).
• weight less than 37 pounds

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (10)

The Ohio State University; 🇺🇸 Columbus, Ohio, United States

University of Texas Southwestern Medical Center at Dallas; 🇺🇸 Dallas, Texas, United States

Shepherd Center; 🇺🇸 Atlanta, Georgia, United States

University of Massachusetts Medical School; 🇺🇸 Worcester, Massachusetts, United States

Johns Hopkins; 🇺🇸 Baltimore, Maryland, United States

Beth Israel Deaconess; 🇺🇸 Boston, Massachusetts, United States

Barrow Neurological Institute; 🇺🇸 Phoenix, Arizona, United States

The Rocky Mountain MS Center at Anschutz Medical Campus at UC Denver; 🇺🇸 Aurora, Colorado, United States

Stanford University; 🇺🇸 Stanford, California, United States

Multiple Sclerosis Research Center of New York; 🇺🇸 New York, New York, United States