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The Establishment of Large-sample Database of "Multiple-MRI/Gene/Cognition"

Conditions
Healthy
Interventions
Device: MRI
Registration Number
NCT02144467
Lead Sponsor
Hangzhou Normal University
Brief Summary

Aim to establish a large-sample database of "Multiple-MRI/Gene/Cognition" for healthy Chinese (sample number, 5000; age, 6-70 years). This is a fundamental but very necessary work for future researches such as development, aging, relation of gene and behavior, relation of gene and neuroimaging, relation of behavior and neuroimaging. Importantly, this work will provide a norm for researches on psychological or neurological patients. This large-sample will be shared with world-wide researchers.

Detailed Description

A part of data have been used in a publication which is preparing to submit.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
5000
Inclusion Criteria
  • Healthy Chinese
  • Age: 6-70 years old
  • Right handed
  • No smoking or alcoholic addiction
Exclusion Criteria
  • Psychological or neurological patients
  • Hypertension or cardiopathy patients
  • Pregnant woman
  • Take medicine or drink tea/coffee before scanning-

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Large-sample healthy participantsMRIMRI scanning.
Primary Outcome Measures
NameTimeMethod
The distribution of the amplitude of blood oxygenation level dependent(BOLD) signal in healthy subjectsup to 15 months

The amplitude of BOLD-functional magnetic resonance imaging(fMRI) signal is a common measure to estimate the brain activity during resting-state. We try to establish its distribution on healthy subjects, which could be a control to examine abnormal brain function in patients.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Hangzhou Normal University,Center for Cognition and Brain Disorder

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Hangzhou, Zhejiang, China

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