Effect of selective alpha 1A receptor antagonists on the iris dilator muscle

• Conditions: Effect of selective alpha 1A receptor antagonists on the iris dilator muscle; Therapeutic area: Diseases [C] - Eye Diseases [C11]

• Registration Number: EUCTR2015-003061-28-AT
• Lead Sponsor: Vienna Institute for Research in Ocular Surgery

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-07-24
• Last Update Posted: 21 September 2015

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion criteria for the study group
-Age 21 and older
-Impending initiation of a therapy with systemic selective alpha 1A antagonists
-written informed consent to participation in the study

Inclusion criteria for the control group
-Age 21 and older
-written informed consent to participation in the study

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 46
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Exclusion criteria for the study group
-Pregnancy (pregnancy test will be taken pre-operatively in women of reproductive age)
-previous therapy with systemic selective or non-selective alpha 1A antagonists
-ophthalmic pathologies such as any ophthalmic pathologies or previous ocular surgeries

Exclusion criteria for the control group
-Pregnancy (pregnancy test will be taken pre-operatively in women of reproductive age)
-previous therapy with systemic selective or non-selective alpha 1A antagonists
-ophthalmic pathologies such as any ophthalmic pathologies or previous ocular surgeries

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified