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Design and Implementation of a Drunk Driving Detection System

Not Applicable
Completed
Conditions
Impaired Driving
Transportation Accidents
Drunk Driving
Alcohol Drinking
Interventions
Other: Driving under the influence of alcohol with a driving simulator
Registration Number
NCT04980846
Lead Sponsor
University of Bern
Brief Summary

To analyse driving behavior of individuals under the influence of alcohol using a validated research driving simulator. Based on the driving variables provided by the simulator the investigators aim at establishing algorithms capable of discriminating sober and drunk driving patterns using machine learning neural networks (deep machine learning classifiers).

Detailed Description

Driving under the influence of alcohol (or "drunk driving") is one of the most significant causes of traffic accidents. Alcohol consumption impairs neurocognitive and psychomotor function and has been shown to be associated with an increased risk of driving accidents. Automotive technology is highly dynamic, and fully autonomous driving might, in the end, resolve the issue of alcohol impaired accidents. However, autonomous driving (level 4 or 5) is likely to be broadly available only to a substantially later time point than previously thought due to increasing concerns of safety associated with this technology. Therefore, solutions bridging the upcoming period by more rapidly and directly addressing the problem of drunk driving-associated traffic incidents are urgently needed.

On the supposition that driving behaviour differs significantly between sober and drunk states, the investigators assume that different driving patterns in both states can be used to generate drunk driving detection models using machine learning neural networks (deep machine learning classifiers).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Informed consent as documented by signature.
  • In possession of a Swiss or EU driving license for at least two years.
  • At least driving 1'000 kilometers per year.
  • No special equipment needed when driving.
  • Drinks alcohol at least occasionally (moderate/social consumption).
  • Fluent in (Swiss) German and no speech impairment.
  • Lives in or near Bern.
Exclusion Criteria
  • Health concerns that are incompatible with alcohol consumption.
  • Any potential participant currently taking illegal drugs or medications that interact with alcohol.
  • Women who are pregnant or breast feeding.
  • Intention to become pregnant during the course of the study.
  • Teetotallers (alcohol abstinent persons).
  • Alcohol misuse (excessive alcohol consumption habits/risky drinking behaviour (according to WHO definition) and/or PEth in capillary blood > 210 ng/mL at first visit.
  • Known or suspected non-compliance or drug abuse.
  • Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc. of the participant.
  • Participation in another study with investigational drug within the 30 days preceding and during the present study.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Intervention groupDriving under the influence of alcohol with a driving simulatorIntervention: Other: Driving under the influence of alcohol with a driving simulator
Primary Outcome Measures
NameTimeMethod
Accuracy of the DRIVE-model: Diagnostic accuracy of the drunk driving warning system (DRIVE) to detect drunk driving (>= 0.25 mg/l breath alcohol concentration (BrAC)) quantified as the area under the receiver operator characteristics curve (AUC ROC).480 minutes

Accuracy of the DRIVE-model will be assessed using driving data recorded in sober and drunk driving states and driving data will be analysed using applied machine learning technology for impaired driving detection.

Secondary Outcome Measures
NameTimeMethod
Change of velocity480 minutes

Change of velocity between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of heart-rate variability480 minutes

Change of heart-rate variability between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of spinning480 minutes

Change of spinning between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Defining the alcohol concentration when driving performance is decreased480 minutes

Breath alcohol concentration (mg/l BrAC) when driving performance begins to be impaired will be assessed based on significantly altered driving parameters for drunk driving above the legal limit (\>= 0.25 mg/l BrAC), below the legal limit (\<0.25 mg/l BAC) and sober driving.

Change of wrist accelerometer480 minutes

Change of wrist accelerometer recorded by a wearable between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of ethylglucuronide (EtG) in capillary blood2 weeks

Change of ethylglucuronide in capillary blood between before the study day, before driving, during driving in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed.

Change of steer speed480 minutes

Change of steer speed between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of time driving over midline480 minutes

Change of time over midline between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of steer480 minutes

Change of steer between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of steer torque480 minutes

Change of steer torque between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of gaze regions of interest480 minutes

Change of gaze regions of interest (as amount and duration of speedometer or front shield inspections) between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of heart-rate480 minutes

Change of heart-rate between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Diagnostic accuracy in detecting drunk driving (>= 0.25 mg/l BrAC) quantified as the area under the receiver operator curve (AUC-ROC) using audio data480 minutes

Using audio data recorded by microphones accuracy in drunk driving detection will be analysed with applied machine learning technology.

Change of brake480 minutes

Change of brake between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of swerving480 minutes

Change of swerving between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of gaze behavior480 minutes

Change of gaze behavior (as gaze velocity, acceleration or direction changes) between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Driving performance while being sober, above and within the legal limit480 minutes

Based on significantly altered driving parameters above the legal limit of drunk driving (\>= 0.25 mg/l breath alcohol concentration in Switzerland) driving performance while being sober, above and within the legal limit will be assessed.

Change of electrodermal activity (EDA)480 minutes

Change of EDA between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of skin temperature480 minutes

Change of skin temperature between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of cortisol in capillary blood2 weeks

Change of cortisol in capillary blood between before the study day, before driving, during driving in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed.

Accuracy-comparison of DRIVE-model and DRIVEplus-model480 minutes

Diagnostic accuracy of the drunk driving warning system (DRIVING) to detect drunk driving (\>= 0.25 mg/l BrAC) quantified as the area under the receiver operator characteristics curve (AUC ROC) using only driving parameters (DRIVE-model) will be compared to the DRIVE-model with additional integration of physiological parameters (heart-rate, heart-rate variability, electrodermal activity (EDA), skin temperature, accelerometer, facial expression, gaze behavior, and radar) (DRIVEplus-model)

Change of gaze events480 minutes

Change of gaze events (as amount and duration of fixations or saccades) between drunk driving above the legal limit (\>= 0.25 mg/l BrAC), driving within the legal limit (\<0.25 mg/l BrAC) and sober driving.

Change of oral fluid cortisol2 weeks

Change of oral fluid cortisol between before the study day, before driving, during driving in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed.

Change of ethylsulfate (EtS) in capillary blood2 weeks

Change of ethylsulfate in capillary blood between before the study day, before driving, during driving in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed.

Change of phosphatidylethanol (PEth) in capillary blood2 weeks

Change of phosphatidylethanol in capillary blood between before the study day, before driving, during driving in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed.

Diagnostic accuracy in detecting drunk driving (>= 0.25 mg/l BrAC) quantified as the area under the receiver operator characteristics curve using physiological data480 minutes

Accuracy of drunk driving detection using physiological data (heart-rate, heart-rate variability, skin temperature, EDA, accelerometer) recorded with wearable devices during the study period will be analysed using applied machine learning technology.

Diagnostic accuracy in detecting drunk driving (>= 0.25 mg/l BrAC) quantified as the area under the receiver operator curve (AUC-ROC) using video data480 minutes

Using video data recorded by a camera and a thermal camera accuracy in drunk driving detection will be analysed with applied machine learning technology.

Self-estimation of alcohol concentrations480 minutes

Correlation between self-estimated alcohol concentrations and measured breath alcohol concentrations will be assessed.

Diagnostic accuracy in detecting drunk driving (>= 0.25 mg/l BrAC) quantified as the area under the receiver operator curve (AUC-ROC) using eye-tracking data480 minutes

Using eye-tracking data recorded by a camera and an eye-tracker (to record gaze behaviour) accuracy in drunk driving detection will be analysed with applied machine learning technology.

Self-estimation of driving performance480 minutes

Correlation between self-estimated driving performance and measured driving performance based on significantly altered driving parameters in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed. Driving performance will be assessed with two questionnaires. Driving performance will be assessed with on an absolute 5-point scale from 0-5 (a higher value means higher driving performance).

Self-estimation of workload480 minutes

Correlation between self-estimated workload and measured driving performance based on significantly altered driving parameters in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed. Workload will be assessed an absolute 20-point scale from 0-20 (a higher value means higher workload).

Self-estimation of sleepiness levels480 minutes

Correlation between self-estimated sleepiness levels, measured driving performance, and measured breath alcohol concentrations based on significantly altered driving parameters in sober state, above the legal limit (\>= 0.25 mg/l BrAC), and under the legal limit (\< 0.25 mg/l BrAC) will be assessed. Sleepiness will be assessed on an absolute 7-point scale from 0-6 (a lower value means less sleepiness).

Diagnostic accuracy in detecting drunk driving (>= 0.25 mg/l BrAC) quantified as the area under the receiver operator curve (AUC-ROC) using radar sensor data480 minutes

Using radar sensor data (directed on the body of the driver) accuracy in drunk driving detection will be analysed with applied machine learning technology.

Incidence of Adverse Events (AEs)3 weeks

Adverse Events will be recorded at each study visit.

Incidence of Serious Adverse Events (SAEs)3 weeks

Serious Adverse Events will be recorded at each study visit.

Trial Locations

Locations (1)

University of Bern

🇨🇭

Bern, Switzerland

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