DRKS00003721已完成不适用
Identification of biomarkers sensitive to disease progression in patients with Mild Cognitive Impairment. Two-part Research: Part A - WP5P001 - Part A
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- QUALISSIMA
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 50 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Participants will be (i) healthy volunteers (between 50 and 80 years old) and/or (ii) subjects (between 50 and 80 years old), who will perform a 3T-MRI for reasons such as migraine, headache, auditory or visual symptoms, paresthesias, and whose scan will be negative (see exclusion criteria below). Such subjects will be selected and asked to perform additional sequences according to the part A study protocol.
排除标准
- •-Ischaemic lesions already detected in a previous scan
- •-Head injury with loss of consciousness > 24 hours
- •-Current substance abuse
- •-Current therapy with steroids or current chemotherapy
- •-Loss of weight > 5 kg in the last 6 months
- •-Systemic disease with frequent involvement of the CNS (lupus, HIV, rheumatoid arthritis)
- •-CNS disease diagnosed by a specialist or in treatment (such as epilepsy, ictus)
- •-Cerebral metastasis or CNS primary tumour still benign (except for pituitary microadenoma)
- •-Suspected multiple sclerosis + MRI evidence of white matter lesions
- •-Suspected recent stroke + MRI evidence of infarct
- •-Aneurysm > 10 mm and arteriovenous malformations (except for venous angioma)
- •-Dysgenesia of central nervous system
研究者
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