Effect of neuromuscular blockage status on intraoperative MEPs monitoring during spinal surgery: A retrospective observational study
Not Applicable
Completed
- Conditions
- The condition required spinal surgery
- Registration Number
- JPRN-UMIN000035799
- Lead Sponsor
- MSD Japan K.K.
- Brief Summary
Published
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 366
Inclusion Criteria
Not provided
Exclusion Criteria
1) Patients receiving the following medications known to affect neuromuscular function - Anti-epileptic drug - Oral steroid
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method TOF ratio Successful initiation of MEP MEP amplitude Effect on MEP amplitude amplification
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does neuromuscular blockade status influence MEPs monitoring accuracy during spinal surgery in the JPRN-UMIN000035799 MSD Japan K.K. study?
What biomarkers correlate with reliable MEPs signal detection under neuromuscular blockage in spinal procedures?
Are adverse events linked to neuromuscular blockade management during spinal surgery with intraoperative MEPs monitoring?
How do reversal agents like neostigmine impact postoperative MEPs recovery in spinal surgeries with neuromuscular blockage?
What molecular mechanisms underlie MEPs signal suppression by neuromuscular blocking agents in spinal cord monitoring?