To investigate the correlation between serum bile acid level less than 40 micro mol/L in pregnancies affected with intrahepatic cholestasis of pregnancy(liver problem associated to pregnancy) and maternal and fetal outcomes
Not Applicable
- Conditions
- Health Condition 1: O266- Liver and biliary tract disordersin pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2018/10/016128
- Lead Sponsor
- Max Smart Super Speciality Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Pregnant women presenting with pruritis with elevated liver enzymes
Primigravida or Multigravida
Spontaneous or IVF conception
Singleton or Twins
Exclusion Criteria
History of cholelithiasis
Chronic liver disease
Hepatitis A,B,C,E
Any other cause of raised liver function tests
Dermatological cause of pruritis
Allergic disorder
Pre eclampsia and HELLP
Patient refusal
Patient with pruritis but no elevation of liver enzymes
Pregnancy ending before 24 weeks gestation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate maternal and neonatal outcomes in Intrahepatic Cholestasis of pregnancy with Serum Bile Acids less than 40 micro mol per litre <br/ ><br>Timepoint: Until delivery
- Secondary Outcome Measures
Name Time Method To determine the frequency of serum bile acid measurement in these patientsTimepoint: 2 weeks;To determine the optimal timing of delivery with close monitoring in these patientsTimepoint: 40 weeks gestation