Optical Quantification of Breast Density Changes Due to Hormone Treatment, Pregnancy and Breast-feeding.
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Breast Cancer
- 发起方
- University Health Network, Toronto
- 入组人数
- 300
- 试验地点
- 1
- 状态
- 已完成
- 最后更新
- 14年前
概览
简要总结
The purpose of this study is to test the ability of a technique called Transillumination Breast Spectroscopy (TIBS) to monitor an individual's breast density changes over time.
详细描述
Breast density is an established physical risk factor for breast cancer, applicable to the entire female population in a pre-breast-screening program and, unlike other risk factors, was shown to be affected by an intervention treatment. High breast tissue density is associated with increased risk of breast cancer. Transillumination Breast Spectroscopy (TIBS) uses a white light to provide spectral information on breast tissue density and composition (e.g. water, lipid, hemoglobin and other biomolecules). The overall goal of the TIBS program is to develop a technique that can identify individuals at high risk for breast cancer who would benefit most from improved screening methods and a risk reducing intervention (e.g. diet and lifestyle changes) and can monitor the efficacy of the risk reducing intervention itself in an individual. In a previous study, we demonstrated a high correlation between breast density assessed by TIBS and density identified by x-ray mammography. The current study is testing TIBS ability to monitor changes in an individual's breast density over time
研究者
入排标准
入选标准
- •Be in good health and able to provide consent
- •Be between 25 and 45 years of age
- •Be pre-menopausal
- •Are willing to come in to Princess Margaret Hospital (Toronto, Ontario, Canada) for up to 12 visits at intervals of about three months
排除标准
- •Have had a full term pregnancy
- •Have had breast biopsy
- •Have had breast augmentation or reduction
结局指标
主要结局
未指定