Atorvastatin(drug used to lower LDL cholesterol) as an add on therapy in Migraine Prophylaxis(prevention)
Not Applicable
- Conditions
- Health Condition 1: G431- Migraine with aura
- Registration Number
- CTRI/2021/04/032998
- Lead Sponsor
- Arun kumar V
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
•Patients diagnosed with Migraine headache and on prophylaxis
•4 to 15 migraine attacks per month in the past 2 months
Exclusion Criteria
•Patients with Headache other than migraine
•Patients with chronic daily headache (>=15 days/month)
•Patients already on statins for any other conditions
•Patients on any lipid lowering substances
•Patients with renal disease (GFR >than 30ml/min)
•Creatinine kinase > 3 times the upper limit of normal
•Patients with AST/ALT >2 times the upper limit of the normal
•Pregnant, nursing and potentially could become pregnant patients
•Patients with history of any drug/substance abuse or dependence
•Patients with uncontrolled DM, Thyroid disease and psychiatric illnesses
•Known hypersensitivity to statins
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients with more than 50% Reduction in Frequency of attacks at the end of 3rd month of the study <br/ ><br>Timepoint: at the end of 3 months
- Secondary Outcome Measures
Name Time Method Reduction in Severity of pain intensity at the end of 3rd month of the studyTimepoint: at the end of 3 months