European/Australasian Stroke Prevention in Reversible Ischaemia Trial

Not Applicable

Completed

• Conditions: Ischaemia; Circulatory System; Transient ischaemic attack

• Registration Number: ISRCTN73824458
• Lead Sponsor: niversity Medical Center Utrecht (Netherlands)

Brief Summary

1. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16714187 2. 2012 results in http://www.ncbi.nlm.nih.gov/pubmed/22642755

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2004-09-28
• Study Completion: 2006-12-01
• Last Update Posted: 18 May 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 2739

Inclusion Criteria

1. Patients presenting in the participating hospitals with a transient ischaemic attack (TIA) or non-disabling stroke of atherosclerotic origin
2. Randomisation within 6 months after the TIA or minor stroke
3. Modified Rankin scale of 3 or less

Exclusion Criteria

1. (Contra)indication to, or intolerance to, anticoagulants, dipyridamole, or aspirin
2. Disease expected to cause death within weeks or months
3. Source of embolism in the heart
4. Moderate or severe ischemic damage to the white matter of the brain (leukoaraiosis)
5. Anemia, polycythemia, thrombocytosis, or thrombocytopenia
6. Planned carotid endarterectomy
7. Intracranial bleeding or cerebral tumour
8. TIA or stroke caused by vasculitis, migraine, or dissection
9. Severe hypertension
10. Liver failure
11. Pregnancy
12. Chronic alcohol abuse

Study & Design

• Study Type: Interventional
• Study Design: Not specified