A clinical trial to study the effects of a drug Ketamine ,in treatment of patients with depression.

Phase 3

• Conditions: Health Condition 1: F331- Major depressive disorder, recurrent, moderateHealth Condition 2: F321- Major depressive disorder, singleepisode, moderateHealth Condition 3: F322- Major depressive disorder, singleepisode, severe without psychotic features

• Registration Number: CTRI/2024/01/060984
• Lead Sponsor: Dr Susanta Kumar Padhy

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

All patients coming for treatment at the OPD and IPD of the Department of Psychiatry fulfilling the following are included:

a) People with Moderate to Severe Depressive episode according to criteria in DSM 5 and ICD 10 RCD.

b) Aged between 18 to 65 years

c) American Society of Anaesthesiologists (ASA) score of 1, 2

or stable 3

d) With Informed consent from the Legally Authorised Relative

Exclusion Criteria

a.Severe hepatic or renal impairment

b.Uncontrolled hypertension, history of significant cardiac arrhythmias, history of substance dependence, history of seizure disorder or organic brain disorder, pregnancy or breastfeeding

c.Concomitant psychotic disorder.

d.Non-Consenting

e.History of ketamine allergy

f.Receipt of ECT or ketamine in the past 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified