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The effect of Artichoke on fatty liver indices

Phase 2
Conditions
on alcoholic Fatty Liver.
Fatty (change of) liver, not elsewhere classified
Registration Number
IRCT20130126012278N3
Lead Sponsor
Vice Chancellor for Research, Hamedan University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
100
Inclusion Criteria

30-65 years old
Detection of Non-alcoholic Fatty Liver based on high levels of ALT and AST enzymes
Ultrasound diagnosis of Fatty Liver
BMI was more than 25
People who did not Use Antioxidant complementary during a month before sampling
People who had not underlying diseases like heart acute disease, kidney, infections, diabetes, hepatitis B or C and other diseases of the liver
Not having a severe weight losing or gaining regimens within 3 months before sampling
Not using of effective drugs on weight during 3 months prior to sampling
Not using drugs that are likely to be related to this disease (methotrexate, amiodarone, tamoxifen, corticosteroids, valproic acid)

Exclusion Criteria

Pregnancy and lactation
Alcohol drinking
other liver diseases
Diet or treatment for fatty liver in the last 3 months
Autoimmune diseases and cancer
Reluctance to continue research

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
iver enzymes. Timepoint: At the beginning of study, 48 hours after the end of the study (this study will take 7 weeks). Method of measurement: blood assay results (including AST and ALT).
Secondary Outcome Measures
NameTimeMethod
The amount of liver fat accumulation. Timepoint: 45 days. Method of measurement: Doppler color ultrasound.;Liver Enzymes. Timepoint: 45 days. Method of measurement: Blood examination Results.
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