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临床试验/NCT07135063
NCT07135063尚未招募不适用

Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

Marmara University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年10月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
试验地点
1
主要终点
Establish the presence or absence of cranial nerve involvement in BD.

研究概览

简要总结

The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance.

The main questions this study will address are:

  • Do people with BD have changes in cranial nerve function compared to healthy individuals?
  • Are these changes linked to disease duration, symptoms, or lab results?

Participants will:

  • Answer questions about their medical history and BD symptoms
  • Complete questionnaires on daily function, mood, and autonomic symptoms
  • Have a clinical examination of all 12 cranial nerves
  • Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged 18-75
  • Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group)
  • Healthy with no relevant medical history (control group)

排除标准

  • Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy)
  • Other rheumatologic or autoimmune diseases
  • Psychiatric disorders, alcohol/substance abuse
  • Pregnant women
  • Use of pacemakers or recent botox to masseter muscle

结局指标

主要结局

Establish the presence or absence of cranial nerve involvement in BD.

时间窗: Once: Upon patient inclusion

Upon patient inclusion EMG and clinical examination is carried out

次要结局

  • Investigate relation between disease duration (months) and cranial nerve involvement in BD patients(Once: Upon patient inclusion)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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