NCT04783701招募中不适用
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
University Hospital, Linkoeping6 个研究点 分布在 2 个国家目标入组 360 人开始时间: 2021年5月17日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 360
- 试验地点
- 6
- 主要终点
- Graft patency after CABG
研究概览
简要总结
The purpose of this study is to compare the presence of graft patency in single aspirin vs dual anti platelet therapy (DAPT) treatment including ticagrelor in patients with acute coronary syndrome (ACS) treated with coronary artery bypass surgery (CABG). Follow up time is 12-36 months postoperatively and the patency will be evaluated with coronary computed tomography angiography (CCTA)
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Previously included in TACSI-trial
排除标准
- •Highly irregular heart rhythm (i.e. atrial fibrillation)
- •Chronic kidney disease with estimated glomerular filtration rate (eGFR) <45ml/min/1,73m2
- •Body weight >120 kg
- •Previous severe allergic reaction (i.e. anaphylactic reaction) to iodine-based contrast agents
- •Not able to communicate
- •Not willing to participate
结局指标
主要结局
Graft patency after CABG
时间窗: 12-36 months
Defined as patency on CCTA (FitzGibbon A) without previous graft failure identified on CCTA and/or invasive coronary angio (ICA) since CABG, intention to treat (ITT) analysis.
次要结局
- Graft patency after CABG(12-36 months)
- Graft patency after CABG - PP analysis(12-36 months)
研究者
Jonas Holm
MD, PhD
University Hospital, Linkoeping
研究点 (6)
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