Clinical Applicaitons of Non-Invasive Brain Stimulation for the Treatment of Chronic Pain
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Sponsor
- Stanford University
- Locations
- 2
- Primary Endpoint
- Change in Average Daily Pain
Study Overview
Brief Summary
The purpose of this study is to test whether non-invasive brain stimulation, such as Transcranial Magnetic Stimulation (TMS) may alleviate pain associated with various chronic pain conditions. We will test various methods of TMS to identify a treatment approach that may reduce the symptoms of chronic pain for the patient.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age 18 or older
- •Patient with Chronic Low Back Pain
- •Meets minimum pain level criteria
- •Ability to perform the experimental Task and Procedures
Exclusion Criteria
- •MRI contraindication if an MRI exam is required per protocol
- •TMS Contraindication
- •History of a psychological or psychiatric disorder that would interfere with study procedures, at the discretion of the researcher.
- •Neurologic illness that would interfere with brain integrity
- •Current medical condition or medication use that would interfere with study procedures or data integrity, at the discretion of the researcher.
- •Currently pregnant or planning to become pregnant.
- •On going legal action or disability claim.
Outcomes
Primary Outcomes
Change in Average Daily Pain
Time Frame: Baseline Compared to each treatmeant series (at 4 weeks, 8 weeks, and 12 weeks)
Compared to baseline pain report as provided by Visual Analogue Scale (VAS)
Change in Worst Daily Pain
Time Frame: Baseline Compared to each treatment series (at 4 weeks, 8 weeks, and 12 weeks)
As compared to baseline worst daily pain report provided on visual analogue scale (VAS)
Secondary Outcomes
No secondary outcomes reported
Investigators
Sean Mackey
Chief, Division of Pain Medicine
Stanford University