Randomised double blinded comparative study of the effects of Intravenous lignocaine infusion and Caudal Bupivacaine in pediatric laparoscopic surgeries.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Total fentanyl requirement intraoperatively and postoperatively and time to first rescue analgesia from the time of extubation
研究概览
简要总结
The study aims to compare the efficacy of intravenous lignocaine given as 1.5 mg/kg bolus over 5 minutes followed by 1.5 mg/kg/hour infusion, with caudal bupivacaine 2.5 mg/kg prepared to 1.2 ml/kg, in 100 pediatric patients in the age group of 6 months to 6 years, undergoing laparoscopic abdominal surgeries with 50 patients in each group allocated randomly. The total intravenous fentanyl requirement both intraoperatively and postoperatively, time to first rescue analgesia after extubation, heart rate, systolic and diastolic blood pressure at various time points, pediatric anaesthesia emergence delirium score and FLACC Pain score in the postoperative period will be noted to compare the effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 6.00 Month(s) 至 6.00 Year(s)（—）
- 性别
- All
入选标准
- •AMERICAN SOCIETY OF ANAESTHESIOLOGISTS GRADE 1 AND 2 CHILDREN LAPAROSCOPIC ABDOMINAL SURGERIES WEIGHING 10- 20 KILOGRAMS.
排除标准
- •HISTORY OF ALLERGY TO LOCAL ANAESTHETICS HISTORY OF SEIZURES HISTORY OF CARDIAC DISEASES.
结局指标
主要结局
Total fentanyl requirement intraoperatively and postoperatively and time to first rescue analgesia from the time of extubation
时间窗: T Extubation-at extubation total fentanyl used | T postoperative 2 hours- total fentanyl used postoperatively in 2 hours | T rescue- Time from extubation to first rescue analgesia
次要结局
- Heart rate, Systolic blood pressure and Diastolic blood pressure(T0 (baseline), T1 (at the time of port insertion), Tpeak (maximum reading during the procedure), T2 (at extubation), T3(postoperative- 0 min), T4(postoperative- 5 min), T5(postoperative-15 min), T6(postoperative- 30 min), T7( postoperative- 1 hour), T8(postoperative- 2 hour))
- Pediatric anaesthesia Emergence delirium score and Face,Legs,Activity,Cry Consolability FLACC pain scale(At awakening,At postoperative 30 minutes, 1 hour and 2 hour)